Abnormal Autologous Mixed Lymphocyte Reaction in Autoimmune
نویسندگان
چکیده
The autologous mixed lymphocyte reaction (auto-MLR) measures the ability of non-T cells to stimulate autologous T cells to proliferate in tissue culture. The auto-MLR was studied in 1 1 patients with autoimmune thrombocytopenic purpura (ATP). Seven patients had decreased auto-MLR. which averaged 4440 ± 3364 cpm (SEM) compared to 1 5.360 ± 6905 cpm for simultaneously studied controls. The average of the ratios of cpm incorporated by patients/cpm incorporated by control subjects was 0.20 ± 0.06 ( p < 0.01 ). Serum from all 7 patients with low auto-MLR decreased the auto-MIR of normal subjects by
منابع مشابه
Abnormal autologous mixed lymphocyte reaction in autoimmune thrombocytopenic purpura.
The autologous mixed lymphocyte reaction (auto-MLR) measures the ability of non-T cells to stimulate autologous T cells to proliferate in tissue culture. The auto-MLR was studied in 11 patients with autoimmune thrombocytopenic purpura (ATP). Seven patients had decreased auto-MLR, which averaged 4440 +/- 3364 cpm (SEM) compared to 15,360 +/- 6905 cpm for simultaneously studied controls. The aver...
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